Research Publications

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Vorasidenib in IDH-mutant low grade gliomas (Research Article)

This is a research paper and summary about a study (INDIGO trial) using a medication called Vorasidenib in over 300 patients with grade 2 glioma who had an IDH mutation. The research showed the drug significantly slowed tumour growth in the patients taking Vorasidenib compared to patients taking a placebo, and suggests there may be a new treatment…

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Clinical Trial Participation can Extend Survival for Glioblastoma Patients (Research Article)

This study compared the survival of patients with glioblastoma (GBM) who participated in clinical trials to those who didn’t. It found that survival is extended for trial participants and encourages enrolment in clinical trials where this is possible. The article provides a lot of statistics on factors that impact survival such as age…

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Australian Brain Cancer Statistics (Australian Institute of Health and Welfare)

This Australian Government website provides a summary of some high-level brain cancer statistics, including statistics about numbers of new cases, survival rates, incidence, prevalence and deaths from brain cancer in Australia. The data is sourced from the Australian Institute of Health and Welfare's (AIHW) Cancer Data in Australia 2021 web…

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Radiotherapy plus Temozolomide for Glioblastoma (Research Article)

Brief summary of the research publication for patients and carers, and link to the full text research publication for those who like to read all the details.

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Research publication: Evidence-based recommendations on categories for extent of resection in diffuse glioma (European Journal Cancer 2021)

Brief summary of the research publication for patients and carers, and link to the full text research publication for those who like to read all the details.

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First ideas for this online platform (Research Article)

This is our second research paper leading to the development of BT-online. Health professionals at The Royal Melbourne Hospital asked patients with a brain tumour how they would use an online platform specific for people affected by a brain tumour and what their preferences were to manage their disease. Read the survey details and participant…

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Intraoperative Stimulation Mapping (ISM) during Glioma Surgery (Research Article)

This research article compared the outcomes of patients with a glioma who had brain surgery with or without intraoperative stimulation brain mapping (ISM). Patients who had glioma resection with ISM had fewer occurrences of late neurological deficits and more frequently tumour tissue could be removed completely during the surgery.

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Exercise for Patients with Glioblastoma (Research Articles)

A team of Australian researchers explored the perceptions of patients with a glioblastoma and their carers who jointly participated in an exercise program. They further conducted a feasibility study to identify the preliminary efficacy of supervised and tailored exercise on muscle strength, function, fatigue and quality of life in patients with…

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CAR T-cell Therapy and Glioblastoma (Research Articles)

We present a few articles reporting on the latest research into CAR T-cell therapy to treat glioblastoma. An excellent overview article summarises various approaches of CAR T-cell therapy. Other articles report on clinical trials with small numbers of patients, ranging from 3-6 participants. While most tumours recurred after treatment has concluded…

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Ketogenic Therapies for Glioblastoma (Research Article)

A ketogenic diet is a diet comprised of reduced sugar and carbohydrate intake. Is it beneficial for patients with a glioblastoma (GBM) to go on such a diet and is it safe? This research article reviews the available literature on pre-clinical (mice) studies and clinical (human) studies to identify if the ketogenic diet could be an adjuvant therapy…

Vorasidenib in IDH-mutant low grade gliomas (Research Article)

Clinical Trial Participation can Extend Survival for Glioblastoma Patients (Research Article)

Australian Brain Cancer Statistics (Australian Institute of Health and Welfare)

Radiotherapy plus Temozolomide for Glioblastoma (Research Article)

Research publication: Evidence-based recommendations on categories for extent of resection in diffuse glioma (European Journal Cancer 2021)

First ideas for this online platform (Research Article)

Intraoperative Stimulation Mapping (ISM) during Glioma Surgery (Research Article)

Exercise for Patients with Glioblastoma (Research Articles)

CAR T-cell Therapy and Glioblastoma (Research Articles)

Ketogenic Therapies for Glioblastoma (Research Article)

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