Summary
The article provides a good overview of tumours growing from glial cells, and explains the link between gut microbiome and glioma. In three parts, the authors (1) go into great detail of the specific metabolites and their effect on glioma, (2) describe the effect of the gut microbiome on the immune microenvironment of glioma and (3) discuss the presence of intratumoral microbiome in glioma. In short, the gut microbiome can have a promoting as well as inhibiting effect on glioma cells and further reserach is needed to better understand how the microbiome can be used in indiviualised therapies for brain cancer.
It is not the aim of the article and hence no surprise that you won’t find any recommendations on what to eat to best support your microbiome to strengthen its therapeutic effect on brain tumour cells. If you want to hear some advice on that, have a listen to Judith Lacey, guest speaker at our Q&A Webinar: Exercise, Nutrition, & Wellbeing from minute 30:00.
Full text
The full text is attached below.
Research publication
Liang, J., Li, T., Zhao, J., Wang, C., & Sun, H. (2022). Current understanding of the human microbiome in glioma [Review]. Frontiers in Oncology, 12. https://doi.org/10.3389/fonc.2022.781741